Tripterygium wilfordii, also known as Thunder god vine and at other times under the name lei gong teng, represents a vine plant which was extensively used in the Chinese traditional medicine. For more information about Celastrol, please read What is Celastrol. In the ancient times, it was primarily employed as a treatment for edema, chills, and fever while it also saw extensive use as a pain reliever. The basic notion of its use was the balancing of the yin and the yang, allowing the flow of natural energies of the body to heal inflammation or overactivity of the patient’s immune system. In the modern times, especially in the last couple of decades, the same substance in the form of Tripterygium wilfordii extract 98% Celastrol began to be tested and investigated as a potential remedy for a wide range of different conditions and medical issues. Tripterygium wilfordii extract 98% Celastrol side effects and impact was studied in conditions which include arthritis, chronic hepatitis, kidney disease, cancer, and obesity, along with several types of skin disorders.
At the same time, it is currently tested for its short-term ability to act as an anti-fertility compound for men. If this last notion should prove correct, the same Tripterygium wilfordii has a potential to be the basis for an oral contraceptive product that will be used exclusively by men. The use of this plant has shown that in both human and animals, low doses of its extract have the ability to lower the density of the sperm without having big side effects.
In the modern use, this substance has been used for the purpose of managing excessive periods of menstrual bleeding and problems with autoimmune diseases. These conditions include rheumatoid arthritis, lupus, and multiple sclerosis. Tripterygium wilfordii extract 98% Celastrol is also used by being applied directly onto the skin in the case rheumatoid arthritis.
Tripterygium wilfordii extract 98% Celastrol side effects have also been researched thoroughly, but many still remain unknown thanks to the fact that the plant is used for so many distinctly different medical conditions. The main side effect that was discovered is the plant’s ability to act as an immunosuppressant at larger doses. Also, while other substances that are present in the compound might carry their own side effects, 98% extract should exclude all of them. Other side effects include an upset gastrointestinal track in users, which lead to occurrences of diarrhea and nausea. Both will not produce any long-term damage in a majority of users, but can be a source of discomfort.
When it comes to the side effects, male and female infertility which was connected to large doses of the plant’s extract was also noticed in the studies of Tripterygium wilfordii. In 2012, China’s official Food and Drug Administration cautioned the public about the tripterygium wilfordii extract 98% Celastrol potentially harmful side effects, but did not ban its use. During pregnancy, use of the plant’s extract is completely forbidden because testing has proven it to be embryo toxic to mice in laboratory conditions. This means that the same side effect is more than likely in human users as well.
Essentially, tripterygium wilfordii extract 98% Celastrol side effects mainly include gastrointestinal issue and possible infertility at moderate doses. At the same time, it has to be said that the same side effects might have resulted from processing technique that was not adequate and which contaminated the substance with other active and harmful components.